Welcome to the Wendler Lab
Structure and Function of Multiprotein ATPase Motor Assemblies
We investigate the mechanism of force generation in molecular motor proteins of the AAA+ family using single particle cryo electron microscopy. Our main interests are ATPase complexes of the chaperone subgroup, which are responsible for timely destruction or remodeling of their protein substrate. Our aim is to determine high resolution structural snapshots of the assemblies in different physiological states in order to deduce their conformational dynamics. In combination with biophysical and biological techniques the data ultimately lead to a refined mechanistic and functional model of the motor complexes.
Please note: The research group has moved to Potsdam University.
New contact details:
Prof. Dr. Petra Wendler
Institut für Biochemie und Biologie
D-14476 Potsdam- Golm
phone: 0049 331 9775130